PROJECT
Metals has been used in medicine for years, i.e. for stents manufacturing that widen vessels lumen in arthrosclerosis disease. Today’s golden standard is the application of special coatings on stents that release drugs moderating interactions between metal surface and patients’ tissues. However, according to the newest knowledge, drugs releasing is connected with a health risk as well. Because of this, proposing a new, stable, biocompatible coating that would not need pharmacological assistance is a needed goal. So far in the present project the electrochemical method of obtaining polymer coating for metals was developed. The coating exhibits great biocompatible and hemocompatible properties. Further coating modification was also elaborated, which includes covalent bonding of peptides recognized by human endothelial cells.
Such hybrid material is believed to perform like a natural tissue. The method of metals coating is promising in terms of industrial application. Subsequently, more biological studies are planned.
The project "Modification and endothelialization of metal surfaces" is a part of PRELUDIUM programme of National Science Centre, Poland, project no 2013/11/N/ST8/00636.
